Coronavirus pandemic is a global challenge and combine efforts are imperative to contain the spread of this pandemic. The incumbent government is taking corrective measures to minimize the impact of Covid-19. China-Pakistan cooperation against Covid-19 challenge is highly appreciable. Virologists have been struggling to invent a vaccine to treat COVID-19. Coronavirus is an unprecedented pandemic and more research is required in this filed to find a cure and deal with such situation in the future. South Asians countries, like many other developing nations, are unable to fully grasp these biosecurity challenges. The South Asian leadership must cooperate with each other. Regional and international cooperation at this point is imperative for controlling the spread of the deadly virus.