He is perhaps best known for establishing Islamia College‚ Peshawar‚ the first education institution in Peshawar Pakistan‚ on the mould of Sir Syed Ahmad Khan's policy of educating Muslims.
Sahibzada Sahib started his career as a civil servant but he eventually turned into a great educationist and respected politician.
In 1887‚ Sahibzada Abdul Qayyum was appointed Naib Tehsildar and subsequently held several administrative portfolios i.e. Tehsildar‚ Chief Political Agent of Hazara‚ Revenue Assistant and Treasury Officer‚ Extra Assistant Commissioner‚ Superintendent of the Commissioner's Vernacular Office‚ Assistant Political Agent Khyber‚ 'Assistant Political Agent' of Chitral‚ and then of Khyber Agency and then promoted to Assistant Political Agent of Khyber‚ FATA‚ during the period from 1891 to 1919.
In the year 1893 during rule of Amir Abdur Rahman Khan of Afghanistan a Royal Commission for setting up of Boundary the Durand line between Afghanistan and the British governed India was set up to negotiate terms with the British and the two parties camped at Parachinar.
Sahibzada Abdul Qayyum became the first Chief Minister of the Khyber-Pakhtunkhwa in 1937.